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DNA nanoswitches find new drug leads faster by measuring protein interactions

In a study published in Science, the researchers used FIND to discover both small molecules and nanobodies, small antibody-like proteins, that promoted particular protein-protein interactions with relevance for different disorders. Many conventional drug screens test compounds individually in multiwell plates, with instruments measuring changes in purified proteins or cells. Pooled…

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More in Nanomaterials & 2D Materials

Preparing Battery Materials for Accurate Particle Size Measurement

Precise characterization of lithium iron phosphate (LFP) particle size distribution (PSD) is essential for increasing the performance of batteries. This investigation examines the problems faced during LFP PSD analysis and presents a customized method using ultrasonication with pre-dispersion. A sequence of tests determined that the ideal pre-dispersion configuration includes ultrasonication…

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