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Enzyme Redesign Turns Photochemistry Into a Route to Chiral Phosphorus Compounds

A repurposed imine reductase uses photoexcited NADP+ to generate P-centred radicals and forge chiral carbon–phosphorus bonds with divergent stereocontrol. Chemists have long struggled to control the handedness of phosphorus-centred radicals, reactive intermediates that could unlock a valuable class of molecules but have stubbornly resisted stereocontrol Now a team writing in…

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A new sensing architecture to detect small molecules

Are you sure you want to import this news into ? Secondary serotonin aptamer (green) binds to the target-bound primary serotonin aptamer (pink). 2026 EPFL CHEMINA CC BY SA EPFL scientists have reimagined how aptamers – short DNA strands used in molecular sensors – detect their targets. Their versatile sensing…

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A New Catalytic Shortcut Turns Nitrogen Into Ammonia with Record Efficiency

Ammonia is essential for global agriculture, but its production via the Haber-Bosch process is energy-intensive and emits vast amounts of CO₂. Electrocatalytic nitrogen reduction offers a greener alternative, yet breaking nitrogen’s stubborn triple bond under mild conditions has remained a major hurdle. Now, researchers have introduced a conceptually novel mechanism—hydroxide-activated…

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More in Hydrogen & Fuel Cells