News
New method streamlines C'N bond formation for amine synthesis
2+ hour, 23+ min ago (338+ words) Researchers at the University of Wisconsin'Madison have reported a new approach to forming carbon'nitrogen bonds, a critical step in the synthesis of amines widely used in pharmaceuticals, agrochemicals and polymers. Scientists at the University of Wisconsin'Madison have developed a catalytic…...
Physics-based modelling offers a new way to study drug targets
4+ week, 2+ day ago (1273+ words) Proteins are often studied as static structures, yet they behave dynamically in living systems. Tiffanwy Klippel-Cooper of Omnigeni Q explains how physics-based modelling could help researchers better understand drug targets. A new approach emerging from Australian start-up Omnigeni Q aims…...
Light-driven chemistry offers faster, greener drug design
1+ mon, 1+ week ago (754+ words) Scientists at the University of Cambridge have developed a light-powered method to modify complex drug molecules without toxic chemicals, enabling faster, cleaner and more efficient drug development. Scientists at University of Cambridge have developed a new technique that uses light…...
Boron compounds offer new method for improving existing drugs
2+ mon, 2+ week ago (552+ words) Researchers have developed a new class of stable boron compounds that could make it easier to improve existing medicines, allowing developers to fine-tune effectiveness without rebuilding drugs from scratch. Researchers at the University of Gothenburg are simplifying drug development by…...
New generative AI method could make drug discovery faster
3+ mon, 1+ day ago (595+ words) A newly developed AI-driven technique could dramatically speed up the discovery of drugs and advanced materials, enabling scientists to design chemically valid, property-targeted molecules in minutes rather than years. A new artificial intelligence technique could significantly accelerate the discovery of…...
New fluorescent technology tracks drug responses in cells
3+ mon, 1+ week ago (456+ words) Researchers have developed new innovative fluorescent labels that allow scientists to observe cellular processes with unprecedented clarity " offering a powerful tool for medicine, drug research and cell biology. Researchers at IOCB Prague have developed a new type of fluorescent label…...
TRPM5 protein switch discovery could lead to new diabetes drugs
3+ mon, 2+ week ago (595+ words) Northwestern University scientists have discovered a hidden "control switch" in the TRPM5 protein, which helps regulate taste, blood sugar and gut health and could lead to new therapies for targeting diabetes and obesity. Northwestern University researchers have identified a previously hidden…...
How Fts Z and Zap A proteins drive bacterial cell division
8+ mon, 3+ week ago (524+ words) Japanese researchers have discovered how the bacterial proteins Fts Z and Zap A work together to drive cell division " a discovery that could guide the development of new antibacterial treatments. A team of Japanese researchers, led by Professor Hiroyoshi Matsumura…...
The science behind the systematic discovery of molecular glues
6+ mon, 4+ week ago (1094+ words) For decades, molecular glues have been stumbled upon rather than designed. A new scientific approach is now changing that " expanding what is considered druggable. We sat down with Dr Jia Lu, Principal Scientist at Phore Most and co-developer of Glue…...
Slowing intracellular transport boosts potential for RNA therapies
9+ mon, 1+ week ago (363+ words) Researchers at the University of Basel and Roche have discovered that slowing the intracellular transport of RNA-based drugs significantly improves their therapeutic impact. Despite their promise, a major limitation of ASOs is that most fail to reach their intended targets…...