3+ hour, 3+ min ago   (209+ words) Getty: Sigrid Gombert / Getty Images Bioinformatics can inform liabilities before even picking up a pipette. Cell line stability, clone selection and high-throughput upstream optimization reduce host cell protein (HCP) accumulation by preventing upregulation of lipases and proteases that cause oxidation…...

2+ week, 6+ hour ago   (297+ words) The collaboration is specifically focused on applying Receptor.AI's computational platform to Sethera's proprietary polymacrocyclic peptide chemistry, encoded screening data, and resulting therapeutic candidates. Each company will retain its background platform technologies. The post Receptor.AI and Sethera Plan to…...

1+ mon, 1+ week ago   (285+ words) Fully-continuous, automated bioprocessing is achievable only when processes are tightly integrated and engineered to eliminate volume mismatches between steps and digitally managed to ensure system-wide visibility and interventions. The post Interface Mismatches Remain Key Barrier to Continuous Bioprocessing appeared first…...

1+ mon, 2+ week ago   (451+ words) Basecamp Research’s antibiotic design and vaccine prediction AI models are now available through Anthropic’s Claude Science By Fay Lin, PhD Anthropic’s life science partners are delivering applications. Basecamp Research is targeting global public health, where drug-resistant infections play a role…...

1+ mon, 3+ week ago   (387+ words) Prions are best known for their role in rare, fatal neurodegenerative diseases. But a new study by researchers at the University of Pennsylvania suggests that proteins in this family may also conceal molecular fragments that can kill bacteria, including drug-resistant…...

3+ mon, 3+ day ago   (660+ words) Researchers engineered E. coli into “cell factories” that sustainably produce the UV-protective fish egg-derived compound gadusol, which could eventually serve as a sunscreen ingredient and an antioxidant additive. The post Synthesizing a Natural Sunscreen and Antioxidant in E. coli appeared first…...

3+ mon, 1+ week ago   (199+ words) Developing new molecular compounds is crucial to address pressing challenges, from drug discovery to sustainable materials. However, discovering viable new molecules is challenging due to the vastness of the search space. CoCoGraph uses a diffusion model, a technique common in…...

3+ mon, 1+ week ago   (404+ words) Genetic Engineering and Biotechnology News Prolific Machines, an Emeryville, CA-based biotech company focusing on light-controllable biomanufacturing powered by optogenetics, reported a productivity milestone of 21 g/L in a 15-day intensified fed-batch CHO run for a monoclonal antibody (mAb). This is…...

4+ mon, 1+ day ago   (849+ words) Proteins.1 launches to commercialize a technology enabling ultra-sensitive detection of proteins at the single-molecule level, with the aim of transforming early disease diagnostics. The post Proteins.1 Launches to Develop Single Molecule Protein Amplification Tech for Diagnostics appeared first on GEN…...

3+ mon, 3+ week ago   (487+ words) Purifying virus-like particles (VLPs) entails multiple existing and emerging technologies, and the recognition that differences among VLP processes themselves significantly affect their success. The post Overcoming the VLP Purification Bottleneck appeared first on GEN - Genetic Engineering and Biotechnology News. Virus-like…...