News
Manipulating Microliter Droplets Without Sticking by Particle Coating
5+ hour, 40+ min ago (160+ words) Credit: Mariya Borisova / 500px The fluid-handling bioprocessing surfaces that successfully repel microliter droplets aren't as effective for nano- and picoliter droplets. Because those smaller droplets are more sensitive to chemical and topological differences in the substrate, they are more likely to…...
Terray’s AI Model Accelerates Drug Potency Prediction, Pose Not Needed
6+ day, 8+ hour ago (530+ words) TerraBind proposes to significantly speed up drug discovery with accurate potency predictions that do not require all-atom structures By Fay Lin, PhD TerraBind predicts drug potency when interacting with a target. [Terray] Jacob Berlin, PhD, CEO of Terray Therapeutics, explains…...
High-Density Fed-Batch Optimization Cuts GLP-1 Bioproduction Costs
1+ week, 5+ hour ago (238+ words) Credit: David Petrus Ibars / iStock / Getty Images Plus Researchers in India have developed a high-density fermentation strategy that significantly increases the yields of recombinant glucagon-like peptides-1 (GLP-1) in Escherichia coli. It may reduce upstream production costs by 2030%. U.S. governmental policy changes…...
Mass Spectrometry’s Expanding Frontier
1+ week, 6+ day ago (181+ words) By Mike May, PhD For McBee of Advanced Materials Technology, the past several years in pharmaceutical science seem transformative. "I feel like we're coming into another sort of golden age of pharmaceuticals," he says, pointing to the explosion in new…...
Cell Lines That Make Their Own Amino Acids
4+ week, 5+ hour ago (327+ words) By Vivienne Raper, PhD Danish researchers have created new cell lines that need a less tailored feeding schedule and produce fewer waste products. The team, from the Technical University of Denmark (DTU), says they've designed Chinese Hamster Ovary (CHO) cell…...
Animal-Free Protein and Enzyme Deal Expanded by Dyadic and Fermbox Bio
2+ mon, 9+ hour ago (465+ words) The Dyadic Applied Solutions agreement will enable Fermbox Bio to manufacture and commercialize a growing portfolio of Dyadic-developed proteins and enzymes using both the Dapibus" and C1 expression systems. The post Animal-Free Protein and Enzyme Deal Expanded by Dyadic and Fermbox…...
Beyond Vaccines: Scaling the Promise of RNA Therapeutics
2+ mon, 2+ week ago (146+ words) From enzymes and lipid nanoparticles to large-scale process design, four global innovators redefine RNA-based medicine development and delivery By Mike May, PhD A lipid nanoparticle used as a delivery device for an RNA-based therapy includes several components: the RNA payload,…...
Adsorption Remains a Sticky Problem
3+ mon, 1+ week ago (366+ words) By Gareth John Macdonald Credit: Extreme Media/ Getty Images Accumulation on surfaces is a big problem for protein drug makers. Such interactions impact drug efficacy and stability and can result in the formation of aggregates that provoke dangerous allergic reactions....
Simpler Approach to Calibrating Raman-Based Models
3+ mon, 3+ week ago (402+ words) By Vivienne Raper, PhD Credit: monsitj/ iStock / Getty Images Plus Swiss researchers have developed a new method to enhance Raman calibration datasets used to create predictive models. The researchers, based at the University of Applied Sciences Northwestern Switzerland (FHNW) near…...
Metal-Organic Frameworks Win the 2025 Nobel Prize in Chemistry
4+ mon, 1+ week ago (365+ words) By Julianna LeMieux, PhD The Nobel Prize in Chemistry 2025 has been awarded for the development of metal-organic frameworks (MOF) to Susumu Kitagawa, PhD, professor at Kyoto University, Japan, Richard Robson, PhD, professor at University of Melbourne, Australia, and Omar M. Yaghi,…...