News
AI Discovers Potential Antimicrobial "Prionin" Peptides
6+ hour, 25+ min ago (387+ words) Prions are best known for their role in rare, fatal neurodegenerative diseases. But a new study by researchers at the University of Pennsylvania suggests that proteins in this family may also conceal molecular fragments that can kill bacteria, including drug-resistant…...
Synthesizing a Natural Sunscreen and Antioxidant in E. coli
1+ mon, 1+ week ago (660+ words) Researchers engineered E. coli into "cell factories" that sustainably produce the UV-protective fish egg-derived compound gadusol, which could eventually serve as a sunscreen ingredient and an antioxidant additive. The post Synthesizing a Natural Sunscreen and Antioxidant in E. coli appeared first on…...
Co Co Graph AI Model Generates Molecules that Comply with Rules of Chemistry
1+ mon, 2+ week ago (199+ words) Developing new molecular compounds is crucial to address pressing challenges, from drug discovery to sustainable materials. However, discovering viable new molecules is challenging due to the vastness of the search space." Co Co Graph uses a diffusion model, a technique…...
Light-Controlled Gene Expression Platform Reportedly Doubles Standard Fed-Batch Manufacturing Performance
1+ mon, 2+ week ago (404+ words) Genetic Engineering and Biotechnology News Prolific Machines, an Emeryville, CA-based biotech company focusing on light-controllable biomanufacturing powered by optogenetics, reported a productivity milestone of 21 g/L in a 15-day intensified fed-batch CHO run for a monoclonal antibody (m Ab). This…...
Proteins. 1 Launches to Develop Single Molecule Protein Amplification Tech for Diagnostics
2+ mon, 6+ day ago (849+ words) Proteins. 1 launches to commercialize a technology enabling ultra-sensitive detection of proteins at the single-molecule level, with the aim of transforming early disease diagnostics. The post Proteins. 1 Launches to Develop Single Molecule Protein Amplification Tech for Diagnostics appeared first on GEN…...
Overcoming the VLP Purification Bottleneck
2+ mon, 13+ hour ago (487+ words) Purifying virus-like particles (VLPs) entails multiple existing and emerging technologies, and the recognition that differences among VLP processes themselves significantly affect their success. The post Overcoming the VLP Purification Bottleneck appeared first on GEN - Genetic Engineering and Biotechnology News. Virus-like…...
Digital Twin Process Could Slash Microbial Protein Costs
2+ mon, 1+ week ago (319+ words) By Vivienne Raper, Ph D A consortium of companies has developed what they call a digital twin of a microbial process to produce protein A. Novasign, based in Vienna, hopes its participation through the ECOnti consortium will help manufacturers slash the…...
Ultra- and Diafiltration Clear Leachables Effectively
2+ mon, 1+ week ago (179+ words) By Mike May, Ph D Credit: Image generated with Google Gemini Although UF/DF has long been assumed to reduce small-molecule contaminants, systematic data have been scarce. To address this gap, the team evaluated 28 representative organic compounds spiked into three…...
Cell Signaling-Inspired DNA Sensor Enables Molecular Detection from Single Blood Drop
8+ mon, 6+ day ago (262+ words) Drawing inspiration from natural cell signaling cascades, chemists at Universit" de Montr"al (Ude M) have developed a DNA-based signaling cascade that allows them to quantify and report via an easily measurable electrochemical signal the concentration of various molecules in a…...
Redefining Bioprocessing Using Reservoirs of Biochemical Diversity
2+ mon, 2+ week ago (263+ words) By Mike May, Ph D Credit: Penpak S. / Getty Images In the global race to improve how medicines are made, scientists are turning to an unlikely source of innovation: the microscopic life thriving in some of the harshest soils on Earth....