News
Digital Twin Process Could Slash Microbial Protein Costs
4+ hour, 17+ min ago (319+ words) By Vivienne Raper, Ph D A consortium of companies has developed what they call a digital twin of a microbial process to produce protein A. Novasign, based in Vienna, hopes its participation through the ECOnti consortium will help manufacturers slash the…...
Ultra- and Diafiltration Clear Leachables Effectively
4+ hour, 17+ min ago (179+ words) By Mike May, Ph D Credit: Image generated with Google Gemini Although UF/DF has long been assumed to reduce small-molecule contaminants, systematic data have been scarce. To address this gap, the team evaluated 28 representative organic compounds spiked into three…...
Cell Signaling-Inspired DNA Sensor Enables Molecular Detection from Single Blood Drop
5+ mon, 4+ week ago (262+ words) Drawing inspiration from natural cell signaling cascades, chemists at Universit" de Montr"al (Ude M) have developed a DNA-based signaling cascade that allows them to quantify and report via an easily measurable electrochemical signal the concentration of various molecules in a…...
Redefining Bioprocessing Using Reservoirs of Biochemical Diversity
1+ week, 18+ min ago (263+ words) By Mike May, Ph D Credit: Penpak S. / Getty Images In the global race to improve how medicines are made, scientists are turning to an unlikely source of innovation: the microscopic life thriving in some of the harshest soils on Earth....
Faster Process Development via "Transfer Learning
1+ week, 4+ hour ago (540+ words) By Gareth John Macdonald Credit: Robert Essel NYC/ Getty Images An emerging artificial intelligence technique called "transfer learning" could help drug makers use data to speed up the development of biopharmaceutical manufacturing processes, according to new analysis. In transfer learning,…...
e Xo Zymes' Cell-Free Biomanufacturing Platform Gets Positive Feedback from Cayman Chemical
3+ week, 6+ day ago (804+ words) e Xo Zymes views Cayman's pilot run as an important validation of its cell-free platform, demonstrating that it performs reliably at scale and delivers strong results in the hands of an external partner. The post e Xo Zymes' Cell-Free Biomanufacturing…...
Simulating Life: 4 D Whole-Cell Model of a Minimal Bacterium
1+ mon, 6+ day ago (630+ words) GEN - Genetic Engineering and Biotechnology News Simulating the complete life cycle of a minimal bacterial cell in 4 D (space and time)from DNA replication to protein translation to metabolism and cell divisionat nanoscale resolution has recapitulated how every molecule within…...
Light-Directed System Accelerates Evolution of Complex Protein Functions
1+ mon, 1+ week ago (612+ words) Scientists have developed a novel protein evolution approach dubbed optovolution that uses light to guide the evolution of proteins with dynamic, multi-state, and computational functions based on. .. Scientists have developed a novel protein evolution approach dubbed optovolution that uses light…...
Upping the Profiling of Chemical Exposures in the Omics Sciences
1+ mon, 1+ week ago (205+ words) Panome Bio, a multi-omics CRO, launched its exposomics service platform that offers chemical exposure profiling in biological samples. The service suite combines two complementary workflows. Discovery Exposomics is powered by Mass ID, the company's computational engine for untargeted LC/MS…...
Manipulating Microliter Droplets Without Sticking by Particle Coating
1+ mon, 3+ week ago (160+ words) Credit: Mariya Borisova / 500px The fluid-handling bioprocessing surfaces that successfully repel microliter droplets aren't as effective for nano- and picoliter droplets. Because those smaller droplets are more sensitive to chemical and topological differences in the substrate, they are more likely to…...