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Pharmaceuticals and Drug Discovery
Pharmaceuticals and Drug Discovery in Chemistry: the news, the names and what changed.
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Scripps Research associate professor Keren Lasker receives DARPA Young Faculty Award to develop “toxin traps”
4+ hour, 7+ min ago (359+ words) In the next Front Row lecture, Christian Diercks explains how chemists accelerate evolution in the lab to engineer potential new medicines. The therapeutic enzymes they create can break down or modify disease-related molecules, leading to more precise, effective medical care....
Particle Engineering Takes Center Stage as Pharmaceutical Formulation Science Heads Toward Translation
1+ hour, 25+ min ago (661+ words) The Journal of Pharmaceutical Investigation has announced a January 2027 special issue on translational advances in pharmaceutical dosage form development, spanning particle engineering, formulation science, scale-up, and Quality by Design, with submissions due June 30, 2026....
Ingenious ‘molecular movie’ finally reveals how penicillin is made
5+ hour, 6+ min ago (545+ words) Essential cookies are enabled by default to give you the best possible site experience. For details on the other cookies we use click on settings, or accept them all. Search the University of Oxford website or search for undergraduate courses…...
Real time molecular movie unlocks secrets of penicillin biosynthesis
5+ hour, 7+ min ago (636+ words) Researchers from the University of Oxford and international collaborators have revealed previously unseen rapid chemical stages in the formation of β-lactam antibiotics like penicillin, offering insights that can support future antibiotic development. The findings have been published today (9 Oct) in…...
Unanticipated intermediates during isopenicillin N synthase catalysis identified by time-resolved X-ray free-electron laser studies
19+ hour, 44+ min ago (422+ words) Nature Catalysis (2026) Cite this article Detailed procedures for cloning of IPNS constructs (Supplementary Table 1), expression and purification of IPNS variants, mass spectrometry, NMR and UV–visible experiments, and synthetic procedures are provided in the Supplementary Information. Clarke, H. T., Johnson,…...
'Molecular Movie' of Penicillin Synthesis Could Inform Future Antibiotic Development
11+ hour, 7+ min ago (278+ words) Researchers from the University of Oxford and international collaborators have revealed previously unseen rapid chemical stages in the formation of β-lactam antibiotics such as penicillin, offering insights that could help to support future antibiotic development. The study brought together expertise…...
X-ray Lasers Catch Penicillin-Making Enzyme in the Act, Revealing Surprise Intermediates
6+ hour, 53+ min ago (749+ words) Bioengineer.org...
How modern synthetic tools are transforming chemistry and drug discovery
8+ hour, 53+ min ago (526+ words) Chemistry is undergoing a profound transformation. While many of the fundamental reactions used in laboratories today have existed for decades, the tools available to researchers are changing rapidly. Electrochemistry is one of the oldest branches of chemistry, dating back to…...
Particle Engineering Takes Center Stage as Journal Seeks Translational Drug Formulation Research
5+ hour, 47+ min ago (617+ words) The Journal of Pharmaceutical Investigation has announced a January 2027 special issue inviting research on particle engineering, formulation science, and translational dosage form development, with submissions due by June 30, 2026....
Molecular Movie Reveals How Penicillin Is Made
14+ hour, 36+ min ago (592+ words) Researchers from the University of Oxford and international collaborators have revealed previously unseen rapid chemical stages in the formation of β-lactam antibiotics like penicillin, offering insights that can support future antibiotic development. The findings have been published today (9 Oct) in…...