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News
Carbon Dots Emerge as a Powerful Weapon Against Superbugs and Biofilms
21+ hour, 3+ min ago (75+ words) A new comprehensive review published in the Journal of Nanoparticle Research surveys one of the most quietly promising corners of nanomedicine: carbon dots, nanoscale specks of carbon that are showing remarkable ability to kill bacteria and dismantle the sticky biofilms…...
Engineered Bacterial Teams Turn Sunlight and CO2 Into 1-Butanol
1+ day, 4+ hour ago (350+ words) Scientists at Uppsala University have taken a significant step toward a long-sought goal in industrial biotechnology: using sunlight and carbon dioxide to feed engineered microbes that churn out valuable chemicals. In a study published in Applied Microbiology and Biotechnology, Stamatina…...
Chemists Deploy Palladium to Switch Off and On a Key Amino Acid in Living
1+ day, 9+ hour ago (703+ words) Phenylalanine rarely gets top billing in discussions of molecular biology, yet this unassuming aromatic amino acid quietly underpins some of the most fundamental processes in the cell....
Chemists forge chiral piperidine mimics in a single asymmetric leap
1+ day, 21+ hour ago (904+ words) Medicinal chemists have long chased a deceptively simple goal: build drug candidates that are less flat, more three-dimensional, and more likely to succeed in the clinic....
A “jack-of-all-trades” enzyme found in American pokeweed: Chinese scientists discover a promiscuous sugar-stitching tool for natural products
3+ day, 10+ hour ago (187+ words) Credit: Zhang Yi, Wang Jinxin, Zhu Yiqing, et al Then came the functional audition: testing each recombinant protein against three triterpene substrates (phytolaccagenin, jaligonic acid, and bayogenin) with UDP-glucose. Only one enzyme passed: PamUGT, converting all three substrates at 30%–40%. Mass…...
Metal-ligand orbital hybridization boosts efficient, long-lasting TADF
4+ day, 1+ hour ago (745+ words) OLEDs Bioengineer.org...
Accelerating antibiotic discovery with ChatGPT
4+ day, 14+ hour ago (409+ words) Dr. César de la Fuente and his team are using new tools in the fight against antimicrobial resistance. “It’s amazing to think about how little we know and how much there is to discover. I try to convey that to…...
OrgAIcat predicts enantioselectivity in organocatalysis using literature data and rapidly optimizes reactions
5+ day, 6+ hour ago (1102+ words) Published chemical literature has accumulated a wealth of reaction data, but this data comes from diverse sources, is unevenly distributed, and is clearly biased towards highly selective "successful experiments." Can such literature data be used for reliable machine learning modeling…...
HKU chemists harness light to build 3D molecular structures for drug discovery
5+ day, 12+ hour ago (479+ words) Researchers from the Department of Chemistry at The University of Hong Kong (HKU), led by Professor Jian HE and collaborators, have developed a new light-driven method for constructing three-dimensional molecular building blocks that could give medicinal chemists greater flexibility in…...
Dr Darren Fayne, DCU School of Chemical Sciences | Dublin City University
6+ day, 19+ hour ago (390+ words) My research uses computation to help identify the design of potential new drugs. I focus on figuring out how potential drugs could interact with proteins. Think of proteins as tiny machines running the body. We have around 20,000 of them, and…...