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BIOENGINEER.ORG - Bioengineering
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News
Engineered Bacterial Teams Turn Sunlight and CO2 Into 1-Butanol
1+ hour, 21+ min ago (350+ words) Scientists at Uppsala University have taken a significant step toward a long-sought goal in industrial biotechnology: using sunlight and carbon dioxide to feed engineered microbes that churn out valuable chemicals. In a study published in Applied Microbiology and Biotechnology, Stamatina…...
Chemists Deploy Palladium to Switch Off and On a Key Amino Acid in Living
5+ hour, 46+ min ago (703+ words) Phenylalanine rarely gets top billing in discussions of molecular biology, yet this unassuming aromatic amino acid quietly underpins some of the most fundamental processes in the cell....
Chemists forge chiral piperidine mimics in a single asymmetric leap
17+ hour, 56+ min ago (904+ words) Medicinal chemists have long chased a deceptively simple goal: build drug candidates that are less flat, more three-dimensional, and more likely to succeed in the clinic....
Metal-ligand orbital hybridization boosts efficient, long-lasting TADF
2+ day, 21+ hour ago (745+ words) OLEDs Bioengineer.org...
New Mixed-Ligand Metal Complexes Show Promise as Antibiotics, Antioxidants
1+ week, 2+ day ago (55+ words) Chemists in Nigeria have unveiled a new family of metal complexes that appear to do several jobs at once: killing bacteria and fungi, mopping up damaging free radicals, slicing through DNA in ways that could inspire future drugs, and even…...
Mild metal-free method enables direct alpha-heteroarylation of amides and
1+ week, 6+ day ago (879+ words) Zinc Powder, Room Temperature, No Palladium: Chemists Awaken a 130-Year-Old Reaction to Build Drug Molecules Every year the pharmaceutical industry fabricates medicines whose molecular backbones share one deceptively simple feature: a carbon atom bearing a three-dimensional substituent stitched directly onto…...
Microwave Chemistry Yields Promising Spiro-Benzothiazole Drug Leads in 20
2+ week, 19+ hour ago (903+ words) A simple mineral catalyst and microwave energy have helped researchers produce a collection of complex drug-like molecules in minutes, while reducing the time required for a conventional synthesis from hours to a fraction of one hour....
Scientists synthesize Z-allylamines using masked alkenyl anions from
2+ week, 1+ day ago (713+ words) Chemists have reported a new way to build stereodefined allylamines, a class of molecules that sits at the intersection of drug discovery, agrochemistry, organic synthesis and advanced materials....
Ligand-Guided Radical Orientation Enables Asymmetric Cyanation of
2+ week, 4+ day ago (623+ words) A new copper-catalysed reaction could give chemists a powerful way to create chiral molecules from some of the most difficult intermediates in organic chemistry: highly reactive, unstabilized alkyl radicals....
Catalysts Enable Asymmetric Carbonyl–Ene Reactions Between Unactivated
2+ week, 5+ day ago (56+ words) A reaction long regarded as one of synthetic chemistry’s most stubborn challenges has moved closer to practical use. In a study published in Nature Catalysis, J.A.A. Grimm, L. Shi, N. Tsuji and colleagues report a catalytic asymmetric intermolecular carbonyl–ene-type…...