Oct 21, 2026, 08:02 ET Research highlights Nu-3's rapid bactericidal activity against clinically relevant resistant pathogens and its potential as a topical treatment for infected diabetic foot ulcers Details of the presentation are as follows: Nu-3 – A Novel, Broad Spectrum Antimicrobial Compound…
Zinc oxide nanoparticles biosynthesized by a Penicillium citrinum endophyte from hibiscus leaves inhibited S. aureus lipase and hyaluronidase, reduced biofilm biomass by up to 68.7 percent and killed the bacterium in laboratory assays.
These monooxygenases depend on partner proteins that shuttle electrons from nicotinamide cofactors into the P450 active site. The structural comparison produced a surprise. Although the M. maydis enzyme, UmaCPR, shares greater sequence similarity with ascomycete CPRs, which include the Candida enzyme, its…
Selenium nanoparticles synthesized with an aqueous extract of the plant Crataegus songarica showed antifungal, anticancer, anti-inflammatory and antidiabetic activity in a new laboratory study, with particle sizes averaging 83 nanometers and strong colloidal stability. A suite of characterization techniques, including FTIR,…
A laboratory study reports that magnesium oxide nanoparticles synthesised with turnip leaf extract inhibited multidrug-resistant Gram-negative bacteria and reduced established biofilms by up to 99 percent.
Researchers have screened a library of porphyrin molecules and their chitosan-bound composites as light-activated antibacterial agents, and found that a small number of silver-metallized composites could inhibit every multidrug-resistant ESKAPE pathogen tested in the laboratory.
A new review finds that silver nanoparticles combined with natural antifungal peptides can inhibit major fruit spoilage fungi, but toxicity and regulatory questions remain unresolved.
Researchers have synthesized cephalosporin-based pronucleotides of AZT that are cleaved by bacterial β-lactamases, achieving a first modest proof of concept for enzyme-triggered antibiotic delivery in resistant Gram-negative bacteria. News Source: Kristina Jarvis. (October 27, 2026). Scientists Build a Cephalosporin Triggered Prodrug That…
"Because metallo-beta-lactamases (which render many clinical strains of bacteria resistant to all penicillin-like antibiotics) contain two metal ions we are able to use a variety of spectroscopic techniques to study them," said Caitlyn Thomas, doctoral candidate in the lab of…
Newswise — By boosting antibiotic uptake and disabling bacterial defense systems, these plant-derived molecules act as potent antibiotic adjuvants, restoring the efficacy of an aging but essential... Plant-Derived Phenolic Acids Revive the Power of Tetracycline Against Drug-Resistant Bacteria Newswise — By boosting…
New chemistry against microbes: antibiotic discovery, antimicrobial and antifungal compounds, and molecules that break bacterial resistance.
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