The new tracer was created by conjugating [¹⁸F]FDG with 4-aminophenylboronic acid, abbreviated PBA. According to the study, the total preparation time was approximately 40 minutes, with a decay-uncorrected radiochemical yield of 10 ± 5 percent across more than three preparations and a radiochemical purity…
A new study shows the PET radioligand AG-120 binds specifically to both wild-type and mutant IDH1, but measured affinities vary strongly with the assay method used. Subject of Research: Binding of the radioligand [18F]AG-120 to wild-type and mutant isocitrate dehydrogenase 1 assessed…
The Dr. Noble Irwin Regional Healthcare Foundation's Radiothon for Healthcare is off to a strong start, raising funds to purchase five pieces of laboratory equipment for Cypress Regional Hospital. Donations have been steadily coming in for the 18th annual radiothon, with…
Cryogenic X-ray fluorescence nanoanalysis reveals that three rhenium anticancer drug candidates with different targeting ligands distribute nearly identically inside cancer cells, while unexpectedly colocalizing with zinc-rich structures.
A carborane-quinazoline hybrid derived from erlotinib delivered boron to tumor cells far more efficiently than BPA and delayed tumor growth in melanoma and lung cancer models, supporting its development as a bifunctional agent for boron neutron capture therapy. Subject of…
Bay to Bay News Tablets for potential radiological incidents available in Delaware City A radiological emergency has never occurred in the area and is highly unlikely, according to the Delaware Emergency Management Agency. You must be a member to read…
Clinical Leader Selecting A Central Lab Network For Radiopharmaceutical Readiness In cooperation with The Bracken Group and Dr. Deepak Behera, MD Radiopharmaceutical trials are still mostly early-stage, with just 10.2% reaching Phase III, but that balance is shifting fast. Most handling…
Hansraj College, University of Delhi, and researchers associated with the University of Chicago are exploring a possible joint research collaboration in radiopharmaceutical chemistry, with cancer diagnosis and treatment emerging as a key area of interest. The proposed collaboration involves the…
MOU sets stage for Korea-based RLT production, wider hospital access, and workforce training Swiss drugmaker Novartis will invest about 140 billion won to build a domestic ecosystem for radioligand therapy (RLT). The plan is to establish local production facilities and increase…
EurekAlert! (From left to right) Tobias Krönke, Dr. Martin Ullrich, and Dr. Constantin Mamat used, among other things, a small-animal PET/CT system for the study to investigate pharmacological properties within the body. HZDR / K. Zheynova More on this News…
Radioactive medicines and imaging agents: radioligand therapy, PET tracers, medical isotope production and the radiochemistry behind them.
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